Advances in Exercise Immunology Book (Copyright 1999)
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Advances in Exercise Immunology Book (Copyright 1999)
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The author of the groundbreaking Exercise and Immunology returns with Advances in Exercise Immunology, a thorough and unparalleled study of the relationship between exercise and immune function.
You'll learn why athletes are susceptible to illness during intense training, how various immune system components respond to exercise, how regular exercise may influence disease progression-including cancer and HIV/AIDS-and whether exercise may help restore immune function in the aged and during space flight.
Advances in Exercise Immunology explores:
whether athletes are more susceptible to illness than the general public;
the effects of exercise on resistance to infectious disease and whether infection adversely influences exercise performance;
the effects of exercise on immune cell function and other mediators of immunity;
the effects of exercise on specific aspects of immune function;
the potential clinical applications of exercise immunology; and
the current state of knowledge and future directions of the field.
The book's organizational structure makes it accessible to readers of differing backgrounds and interests. Researchers and graduate students will appreciate that each chapter is a separate, detailed review of a specific topic. Those new to the field will benefit from the comprehensive overview of all areas of exercise immunology.
Summaries of research findings, practical applications, and areas yet to be explored conclude each chapter and serve as useful review material and thought-provoking guideposts to future study. Introductory readers will find these features helpful in understanding key issues in the field, and graduate students and researchers can use them to extend their own research.
Research efforts in the field of exercise immunology have expanded and intensified as more exercise scientists and health care professionals recognize the importance of this discipline. Advances in Exercise Immunology is the vital resource you need to keep abreast of this flourishing field of study.
About the Author
Dr. Laurel T. Mackinnon has conducted research on the immune response to exercise since 1985 and is internationally recognized for her work on over training and immune function in athletes. She is associate professor in the Department of Human Movement Studies, the University of Queensland, Brisbane, Australia.
In 1992, Dr. Mackinnon authored Exercise and Immunology, the first book to explore the intriguing relationship between exercise and the immune system. She serves as associate editor of exercise and immunology for Medicine and Science in Sport and Exercise and is on the editorial board of Exercise Immunology Review. She has received grant funding for projects related to over training and immune function in athletes.
Dr. Mackinnon is a fellow of Sports Medicine Australia and the American College of Sports Medicine. She is a former board member of the International Society of Exercise and Immunology (ISEI) and the Australian Association for Exercise and Sports Science. In 1997, she served as program chair for the international symposium of ISEI in Germany.
Dr. Mackinnon earned her PhD in exercise science at the University of Michigan. She previously held the position of research assistant professor at the University of New Mexico School of Medicine.
Table of Contents
Preface
Acknowledgments
Chapter 1. Exercise and Resistance to Infectious Illness
Historical Perspectives
Are Athletes Susceptible to Infectious Illness?
Resistance to Experimentally Induced Infectious Illness
Does Acute Illness Affect Exercise Performance?
Practical Considerations for Athletes
Summary and Conclusions
Chapter 2. Overview of the Immune System
General Scheme of the Immune System
Innate and AdaptiveImmunity
Cells of the Immune System
Immunoglobulin and Antibody Phagocytosis
Soluble Factors in the Immune Response
Adhesion Molecules
Overview of Methods to Assess Immune Function
Immune Response to Tumor Cells
Summary and Conclusions
Chapter 3. Exercise and Leukocytes: Number, Distribution, and Proliferation
Leukocyte Number and Subset Distribution
GranulocyteNumber
Lymphocyte Number and Subset Distribution
Exercise and NK Cell Number
Exercise and Monocyte Number
Mechanisms Underlying LeukocyteRedistribution
Summary and Conclusions
Chapter 4. Exercise and Innate Immunity: Phagocytes, Complement, and Acute Phase Proteins
Phagocytic Cells
Soluble Mediators of InnateImmunity
Summary and Conclusions
Chapter 5. Exercise and Humoral Immunity: Immunoglobulin, Antibody, and Mucosal Immunity
Serum Ig and Antibody
The Mucosal Immune System
Mechanisms Underlying Exercise-Induced Changes in Ig and Antibody
Summary and Conclusions
Chapter 6. Exercise and Cytokines
Interleukin-1
Interleukin-2
Interleukin-6
Interferon
Tumor Necrosis Factor-(
Mechanisms Underlying the Cytokine Response to Exercise
Summary and Conclusions
Chapter 7. Exercise and Cytotoxic Cells
Exercise and NK Cells
Exercise and LAK CytotoxicActivity
Exercise and ADCC
Exercise and Monocyte/Macrophage Cytotoxic Activity
Exercise and Cytotoxic T Cells
Summary and Conclusions
Chapter 8. Immune Responses to Exercise: Potential Clinical Applications
Exercise and Cancer
Exercise and Human Immunodeficiency Virus-1 Infection
Aging
Space flight
Dietary Intervention to Boost Immunity in Athletes
Summary and Conclusions
Chapter 9. Exercise and Immunology: Current Knowledge and Future Directions
Current Knowledge
Future Directions
Closing Comments
Glossary
References
Index
About the Author
Audiences
Reference for exercise scientists, sports medicine professionals, and researchers in the fields of immunology, physiology, endocrinology, sports medicine, psychology, and behavioral science.
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Advances in Exercise Immunology Book (Copyright 1999)
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